In an age when advanced technology has declined and a new energy called Magiculture drives the world, humanity once created the forbidden bio-weapons known as Gears. The Gears eventually rebelled, and though humanity barely won the survival war later called the Holy War, the scars remained unhealed over a decade later. Sin Kiske, the child born between a human and a Gear, is on his way to his father Kai and mother Dizzy's wedding, a taboo union between human and Gear. There, a mysterious girl named Unika, who carries Gear blood yet despises Gears, appears, and their encounter sends shockwaves through the world. This is the first-ever TV anime adaptation of the hit fighting game GUILTY GEAR STRIVE.